Cytotoxic activity of extracts from Tecoma species and isolated lignans

A phytochemical study of Tecoma genus (Bignoniaceae) was accomplished by antitumor activity ethanolic extracts. Species this are composed small shrubs often used as ornamental plants. The stans species is in folk medicine for different purposes. Recent work shows vitro anticancer against human breast cancer. extracts from leaves and trunks casneifolia, T. garrocha, var. angustata were tested vitro. assays line tumor cells the MTT method most active further studied. In way, extract presented higher cytotoxicity cell lines studied (CC50 0.02 to 0.55 µg/ml) when compared other 0.08 200.0 µg/ml). Accordingly, selected chromatographic fractionation which five known lignans isolated. Further, paulownin, paulownin acetate, sesamin, olivil cycloolivil identified using 13C 1H NMR, IR, UV spectroscopy spectrometric MS techniques. These isolated compounds exhibited CC50 ranging 13.01 to100.0 µg/ml superior trunk stans.